Effect of guar gum supplementation on lipidic and glycidic metabolic control and body mass index in type 2 diabetes

Revista de Nutrição

Mirela Dos Santos Ourique Figueiredo²  Rita De Cássia Gonçalves Alfenas¹  Sylvia Do Carmo Castro Franceschini¹  Maria Do Carmo Gouveia Peluzio¹  Raquel Monteiro Azeredo¹  Sônia Machado Rocha Rebeiro¹ 

[1] ,Posto de Saúde Dr. José Vieira SerôdioBom Jesus de Itabapoana RJ ,Brasil

关键词: body mass index;    diabetics mellitus Type 2;    guar gum;    metabolic control;    índice de massa corporal;    diabetes mellitus tipo 2;    goma guar;    controle metabólico;   

DOI  :  10.1590/S1415-52732006000200006

来源: SciELO

【 摘 要 】

OBJECTIVE: To evaluate the effects of guar gum supplementation in the metabolic control and body mass index (BMI) of type 2 diabetic patients. METHODS: A total of 17 (12 women and 5 men) participants ingested 10 grams of fiber supplement daily for three months. Changes in BMI and the biochemical parameters (fasting glycemia, glycosilated hemoglobin (HbA1c), total plasma cholesterol and triglycerides) were evaluated at the beginning and the end of the study. RESULTS: No changes in mean BMI (p=0.770), mean fasting glycemia (p=0.09) or triglyceride levels were observed. However, significant increases in HbA1c levels were observed (p<0.001) following the ingestion of guar gum supplements. Posterior analysis indicated that the five participants that had the highest mean fasting blood glucose and HbA1c levels, showed a significant reduction in their fasting glycemic levels (p=0.03) at the end of the study. A significant (p<0.001) reduction in total cholesterol levels was observed after three months of guar gum supplementation. CONCLUSION: Guar gum supplementation (10g/day) in the diet of overweight type 2 diabetics, resulting in total fiber ingestion close to 20g per day, did not lead to a spontaneous reduction in body weight. The effect of guar gum on the glycidic metabolic control was inconclusive, but it was shown to be an effective dietetic strategy to reduce blood cholesterol levels.

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