Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases

Genetics and Molecular Biology

V. Ramana Gopavajhula²  K. Viswanatha Chaitanya²  P. Akbar Ali Khan¹  Jilani P. Shaik¹  P. Narasimha Reddy¹  Mohammad Alanazi¹ 

[1],GITAM University Department of Biotechnology Visakhapatnam,India

关键词: amino acid analysis;    model evaluation;    molecular modeling;    phylogenetic analysis;    superoxide dismutase (SOD);   

DOI  :  10.1590/S1415-47572013005000023

来源: SciELO

【 摘 要 】

Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide. SOD is classified into four metalloprotein isoforms, namely, Cu/Zn SOD, Mn SOD, Ni SOD and Fe SOD. The structural models of soybean SOD isoforms have not yet been solved. In this study, we describe structural models for soybean Cu/Zn SOD, Mn SOD and Fe SOD and provide insights into the molecular function of this metal-binding enzyme in improving tolerance to oxidative stress in plants.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License