Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population

Genetics and Molecular Biology

Zhe Chen²  Xiaofeng Zhao¹  Xiaoling Jiang²  Xiaoling Guo²  Zunzhou Lv²  Hongmei Zhou²  Ningying Xu² 

[1] ,Zhejiang University College of Animal Science ,P.R. China

关键词: PPARγ2 gene;    haplotype;    carcass and meat quality;    pigs;   

DOI  :  10.1590/S1415-47572010005000107

来源: SciELO

【 摘 要 】

The PPARγ2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPARγ2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genotype at the G876A locus. Allele A at the G876A locus was only found in Jinhua pigs. The association between haplotype (A177G/G876A) and carcass and meat quality traits was analyzed in a Pietrain x Jinhua F2 population (N = 248). The PPARγ2 gene was found to be significantly associated with backfat thickness at the shoulder (p < 0.05), 6-7th ribs (p < 0.01), last rib (p < 0.01), gluteus medius (p <0.05) and ham weight (p < 0.01). Significant effects of different haplotypes on ham weight and backfat thickness at the 6-7th ribs, last rib, and gluteus medius were also observed.

【 授权许可】

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