Short-tandem repeat analysis in seven Chinese regional populations

Genetics and Molecular Biology

Xing-bo Song²  Yi Zhou²  Bin-wu Ying²  Lan-lan Wang²  Yi-song Li²  Jian-feng Liu¹  Xiao-gang Bai¹  Lei Zhang²  Xiao-jun Lu²  Jun Wang²  Yuan-xin Ye² 

[1] ,Sichuan University West China Hospital Department of Laboratory MedicineChengdu Sichuan ,China

关键词: forensic medicine;    population genetics;    short-tandem repeat;    human evolutionary history;    genetic distance;   

DOI  :  10.1590/S1415-47572010000400002

来源: SciELO

【 摘 要 】

In the present study, we investigated the application of 13 short tandem repeat (STR) loci (D13S317, D7S820, TH01, D16S539, CSFIPO, VWA, D8S1179, TPOX, FGA, D3S1358, D21S11, D18S51 and D5S818) routinely used in forensic analysis, for delineating population relationships among seven human populations representing the two major geographic groups, namely the southern and northern Chinese. The resulting single topology revealed pronounced geographic and population partitioning, consistent with the differences in geographic location, languages and eating habits. These findings suggest that forensic STR loci might be particularly powerful tools in providing the necessary fine resolution for reconstructing recent human evolutionary history.

【 授权许可】

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