Progressive multifocal leukoencephalopathy restricted to the posterior fossa in a patient with systemic lupus erythematosus

Brazilian Journal of Infectious Diseases

Fabrício Guimarães Gonçalves²  Leslie Lamb²  Raquel Del Carpio-o'donovan¹ 

[1] ,McGill University Health Center Montreal General Hospital ,Canada

关键词: PML;    leukoencephalopathy;    progressive multifocal posterior fossa;    magnetic resonance;    spectroscopy;    diffusion weighted images;   

DOI  :  10.1590/S1413-86702011000600020

来源: SciELO

【 摘 要 】

Progressive multifocal leukoencephalopathy is a neurological infectious disease caused by the John Cunningham polyomavirus (JCV), an opportunistic agent with worldwide distribution. This disease is frequently seen in immunosuppresed patients and rarely associated with systemic lupus erythematosus. In the central nervous system PML demyelinating lesions occur in the supratentorial compartment. The authors describe a rare case of PML secondary to SLE treatment with atypical presentation restricted to the posterior fossa.

【 授权许可】

CC BY-NC-ND   
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