Extensively drug-resistant tuberculosis: a case report and literature review

Brazilian Journal of Infectious Diseases

João Alves De Araújo-filho²  Arioldo Carvalho Vasconcelos-jr²  Eduardo Martins De Sousa²  Colombina Da Silveira¹  Elisangela Ribeiro¹  André Kipnis²  Ana Paula Junqueira-kipnis² 

[1] ,Federal University of Goiás Institute of Tropical Pathology and Public Health

关键词: Extensively drug-resistant tuberculosis;    XDR-TB;    tuberculosis;    Mycobacterium tuberculosis;   

DOI  :  10.1590/S1413-86702008000500019

来源: SciELO

【 摘 要 】

Extensively drug-resistant tuberculosis (XDR-TB) is an emerging health problem that threatens tuberculosis (TB) control worldwide, since suitable treatment for this disease has not yet been found. We report a case of secondary pulmonary XDR-TB in a 54-year-old, HIV-negative male from Goiânia, Brazil. The patient had long-standing pulmonary tuberculosis (nine years) with extensive bilateral lung damage and had been treated with multiple antituberculosis drugs (self-administered) before XDR-TB diagnosis. The strain of Mycobacterium tuberculosis was resistant to R- rifampicin, H-isoniazid, E-ethambutol, Eto-ethionamide, Ofx-ofloxacin, and Am-amikacin. This patient died with multiple organ failure due to sepsis secondary to bacterial pneumonia.

【 授权许可】

CC BY-NC-ND   
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