Use of the D test method to detect inducible clindamycin resistance in coagulase negative staphylococci (CoNS)

Brazilian Journal of Infectious Diseases

Leandro Reus Rodrigues Perez¹  Juliana Caierão¹  Ana Lúcia Souza Antunes¹  Pedro Alves D'azevedo¹ 

[1] ,Foundation of Federal Clinical Medical School of Porto Alegre

关键词: Clindamycin;    resistance;    D test;   

DOI  :  10.1590/S1413-86702007000200002

来源: SciELO

【 摘 要 】

According to the National Committee for Clinical Laboratory Standards (NCCLS, 2004), a method to evaluate the inducible clindamycin resistance in accordance with an approach of the disks of erythromycin and clindamycin - the D test - has been reported. We analyzed the performance of this method in 200 coagulase negative staphylococci (CoNS) strains obtained from blood cultures of hospitalized patients at a general hospital in Southern Brazil. Twenty-seven clinical isolates with suitable profile (erythromycin-resistant and clindamycin-susceptible) were evaluated for the D test realization. Thus, only 5 CoNS were D test positive. The D test method showed to be simple and an important technique in the detection of inducible clindamycin resistance.

【 授权许可】

CC BY-NC-ND   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License