Ibuprofen timing for hand surgery in ambulatory care

Acta Ortopédica Brasileira

Enrico Giuliani¹  Anna Bianchi¹  Augusto Marcuzzi¹  Antonio Landi¹  Alberto Barbieri¹ 

关键词: Ibuprofen;    Analgesics/therapeutic use;    De Quervain Disease;    Trigger finger disorder;    Carpal tunnel syndrome;   

DOI  :  10.1590/1413-78522015230400736

来源: SciELO

【 摘 要 】

OBJECTIVE: To evaluate the effect of pre-operative administration of ibuprofen on post-operative pain control vs. early post-operative administration for hand surgery procedures performed under local anaesthesia in ambulatory care. METHODS: Candidates to trigger finger release by De Quervain tenosynovitis and carpal tunnel operation under local anesthesia were enrolled in the study. Group A received 400 mg ibuprofen before the operation and placebo after the procedure; group B received placebo before the operation and ibuprofen 400 mg at the end of the procedure; both groups received ibuprofen 400 mg every 6h thereafter. Visual analogue scale (VAS) was measured at fixed times before and every 6h after surgery, for a total follow-up of 18h. RESULTS: Groups were similar according to age, gender and type of surgery. Median VAS values did not produce any statistical significance, while there was a statistically significant difference on pre-operative and early post-operative VAS values between groups (A -8.53 mm vs. B 3.36 mm, p=0.0085). CONCLUSION: Average pain levels were well controlled by local anesthesia and post-operative ibuprofen analgesia. Pre-operative ibuprofen administration can contribute to improve early pain management. Level of Evidence II, Therapeutic Studies.

【 授权许可】

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