Outcomes in orthopedics and traumatology: translating research into practice

Acta Ortopédica Brasileira

Vinícius Ynoe De Moraes¹  Paula Martins De Oliveira Ferrari¹  Guilherme Conforto Gracitelli¹  Flávio Faloppa¹  João Carlos Belloti¹ 

关键词: Orthopedics;    Knee joint;    Platelet-rich plasma;    Evidence-based medicine;    Outcomes research;   

DOI  :  10.1590/1413-78522014220601009

来源: SciELO

【 摘 要 】

Clinical research is focused in generating evidence that is feasible to be applicable to practitioners. However, translating research-focused evidence into practice may be challenging and often misleading. This article aims is to pinpoint these challenges and suggest some methodological safeguards, taking platelet-rich plasma therapies and knee osteochondral injuries as examples. Studies and systematic reviews involving the following concepts will be investigated: clinically relevant outcomes, systematic errors on sample calculation, internal and external validity. Relevant studies on platelet-rich plasma for muscle-tendon lesions and updates on osteochondral lesions treatment were included in this analysis. Authors and clinicians should consider these concepts for the implementation and application of dissemination of the best evidence. Research results should be challenged by a weighted analysis of its methodological soundness and applicability. Level of Evidence V, Therapeutic Studies - Investigating the Results of Treatment.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License