Application of expanded inert polytetrafluorethylene membrane in prevention of post laminectomy fibrosis in wistar rats

Acta Ortopédica Brasileira

Tarcísio Eloy Pessoa Barros Filho¹  Cláudia Regina G. C. M. Oliveira¹  Reginaldo Perilo De Oliveira¹  Erika Meirelles Kalil Pessoa De Barros¹  Raphael Martus Marcon¹  Alexandre Fogaça Cristante¹ 

[1] ,Universidade de São Paulo Faculdade de Medicina Hospital das Clínicas

关键词: Laminectomy;    Fibrosis;    Wistar rats;    expanded inert Polytetrafluoroethylene membrane;    Laminectomia;    Fibrose;    Ratos Wistar;    Membrana de Politetrafluoroetileno inerte expandido;   

DOI  :  10.1590/S1413-78522003000200007

来源: SciELO

【 摘 要 】

Post laminectomy fibrosis in spine surgery has been responsible for a high rate of failure in a short or long term. Many of this patients develop chronic or recurrent pain after surgery of discal herniation, canal stenosis etc. Although there some doubts about the etiology of this problem, it was known that fibrosis interfere with the normal mobility of roots and spinal cord. This factor is considered as the most important aspect in the genesis of the surgical failures. To avoid postoperative fibrosis, a lot of materials of interposition between posterior spine muscles and dura mater were studied, without good response. This paper studied comparatively post laminectomy fibrosis in Wistar rats with the addition of the following materials to avoid it: control group (without interposition) and expanded inert polytetrafluoroethylene membrane (Preclude Spinal Membrane®). It was observed that accurate surgical technique apparently is an important factor to prevent the formation of abundant scar tissue and that the expanded inert polytetrafluoroethylene membrane is an inert material.

【 授权许可】

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