Segmental Darier's disease: a presentation of difficult diagnosis

Anais Brasileiros de Dermatologia

Paula Mota Medeiros¹  Natália Ribeiro De Magalhães Alves¹  Jeniffer Muñoz Trujillo¹  Cássia Camarinha Da Silva¹  Paula Carolina Pessanha De Faria¹  Roberto Souto Da Silva¹ 

关键词: Darier's Disease;    Mosaicism;    Skin diseases;    Skin diseases;    genetic;   

DOI  :  10.1590/abd1806-4841.20153581

来源: SciELO

【 摘 要 】

Abstract Darier's disease is a rare autosomal dominant genodermatosis. It has an estimated prevalence of 1 in 55,000 to 100,000 individuals, regardless of gender. It is characterized by multiple keratotic papules on the seborrheic areas of the trunk, scalp, forehead and flexures, and the clinical picture is worsened by heat, sun exposure, perspiration and mechanical trauma. Histopathology observed loss of epithelial adhesion and abnormal keratinization. About 10% of cases present in the localized form of the disease. We report a case of segmental Darier's Disease Type I and discuss the main characteristics of this condition.

【 授权许可】

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