Cutaneous metastases from gastric adenocarcinoma 15 years after curative gastrectomy

Anais Brasileiros de Dermatologia

Fang Liu¹  Wen Liang Yan¹  Haibo Liu¹  Min Zhang¹  Hong Sang¹ 

关键词: Neoplasm metastasis;    Skin neoplasms;    Stomach neoplasms;   

DOI  :  10.1590/abd1806-4841.20153829

来源: SciELO

【 摘 要 】

Abstract We report the case of a 38-year-old man, who developed cutaneous metastases in the left inguinal groove 15 years after curative gastrectomy for advanced gastric adenocarcinoma. Histopathologic examination revealed poorly differentiated adenocarcinoma cells. They were stained positive for villin, CDX-2, CKpan (AE1/ AE3), CEA, CK8/18, CK19, CK7, EMA, Ki-67 (50%), and negative for S-100, CK20, CD34, GCDFP-15 and TTF-1. The patient underwent local excision, after the presence of other metastases was excluded. Nevertheless, local recurrence developed at the surgical bed one year later and PET/CT revealed metastases to lymph nodes, bone and skin. He died 2 years after the appearance of cutaneous metastases. We have reviewed the literature and described the immunohistochemical characteristics of cutaneous metastases from gastric adenocarcinoma.

【 授权许可】

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