Mucosal-dominant pemphigus vulgaris in a captopril-taking woman with angioedema

Anais Brasileiros de Dermatologia

Justyna Gornowicz-porowska¹  Marian Dmochowski¹  Pawel Pietkiewicz¹  Monika Bowszyc-dmochowska¹ 

关键词: Angioedema;    Captopril;    Pemphigus;   

DOI  :  10.1590/abd1806-4841.20153390

来源: SciELO

【 摘 要 】

AbstractWe describe a 39-year-old woman with an apparent captopril-induced, contact mucosal-dominant pemphigus vulgaris and angioedema, who took captopril during a bout of arterial hypertension. This exposure suggests that captopril and pathophysiology of angioedema stimulated the development of pemphigus vulgaris, which was diagnosed using the novel, indirect immunofluorescence BIOCHIP mosaic, with the modification to detect serum IgG4 autoantibodies. We discuss the patient, who experienced a chain of events leading to the active stage of pemphigus vulgaris, and review concepts of pemphigus vulgaris inducible by drugs and pathological immunity.

【 授权许可】

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