Alopecia secondary to anti-tumor necrosis factor-alpha therapy

Anais Brasileiros de Dermatologia

Lara Beatriz Prata Ribeiro¹  Juliana Carlos Gonçalves Rego¹  Bruna Duque Estrada¹  Paula Raso Bastos¹  Juan Manuel Piñeiro Maceira¹  Celso Tavares Sodré¹ 

关键词: Alopecia;    Alopecia areata;    Dermoscopy;    Psoriasis;    Tumor necrosis factor-alpha;   

DOI  :  10.1590/abd1806-4841.20153084

来源: SciELO

【 摘 要 】

Biologic drugs represent a substantial progress in the treatment of chronic inflammatory immunologic diseases. However, its crescent use has revealed seldom reported or unknown adverse reactions, mainly associated with anti-tumor necrosis factor (anti-TNF). Psoriasiform cutaneous reactions and few cases of alopecia can occur in some patients while taking these drugs. Two cases of alopecia were reported after anti-TNF therapy. Both also developed psoriasiform lesions on the body. This is the second report about a new entity described as 'anti-TNF therapy-related alopecia', which combines clinical and histopathological features of both alopecia areata and psoriatic alopecia. The recognition of these effects by specialists is essential for the proper management and guidance of these patients.

【 授权许可】

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