Two cases of renal cell cancer during immunobiologic therapy for psoriasis

Anais Brasileiros de Dermatologia

Fabiana Palmieri Zarur¹  Luiza Ferreira Vieira D'almeida¹  Monique Samy Pamplona Mafort¹  Paula Regazzi De Gusmão¹  João Carlos Regazzi Avelleira¹ 

关键词: Biological therapy;    Kidney neoplasms;    Psoriasis;   

DOI  :  10.1590/abd1806-4841.20143257

来源: SciELO

【 摘 要 】

Immunobiologic therapy is indicated for severe forms of psoriasis, resistant to conventional therapy. There is growing concern about their safety profile and possible association with cancer development. This article documents two cases of renal cell cancer during treatment with biologic therapy, reviewing what is described in the literature . The risk of solid tumors as a complication of using TNF-alpha inhibitors is controversial. No conclusion can be drawn from the data in the literature, however, we believe that special attention should be given to those with known risk factors for a specific neoplasm.

【 授权许可】

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