Case for diagnosis

Anais Brasileiros de Dermatologia

Gustavo Ávila Maquiné¹  Maria De Fátima Maroja¹  Cristina Rabello Mesquita¹  Petra Pereira De Sousa¹  Patrícia Motta De Morais¹  Carolina Talhari¹ 

关键词: B-cell lymphomas;    Legs;    Combination chemotherapy;   

DOI  :  10.1590/abd1806-4841.20142955

来源: SciELO

【 摘 要 】

We report the case of a 81-year-old female patient who had a two-year history of violet-colored erythematous tumors on both legs. Histopathological and immunohistochemical examinations confirmed the diagnosis of primary cutaneous large B-cell lymphoma, leg type. This rare, cutaneous lymphoma affects predominantly elderly females. Clinically, patients present with tumoral lesions on one or both legs (worst prognosis). Diagnosis is based on clinical, histopathological and immunohistochemical findings. The strong expression of BCL2, BCL6, MUM-1 and CD20, and the positivity for Ki67 antigen confirm the diagnosis. R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone) is the most widely accepted treatment.

【 授权许可】

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