Sacroiliitis after use of oral isotretinoin - association with acne fulminans or adverse effect?

Anais Brasileiros de Dermatologia

Ariane Silva Bastos Geller¹  Roberta Ferreira Nazareth Alagia¹ 

关键词: Acne vulgaris;    Arthritis;    Isotretinoin;    Sacroiliitis;    Acne vulgar;    Artrite;    Isotretinoína;    Sacroileíte;   

DOI  :  10.1590/abd1806-4841.20132500

来源: SciELO

【 摘 要 】

Acne fulminans is a rare and severe form of acne that may evolve from acne vulgaris, especially in male adolescents, or occur as an adverse effect of oral isotretinoin. Arthritis is a serious clinical manifestation when the musculoskeletal system is compromised by AF and has been reported as a rare adverse effect of isotretinoin. Involvement of the sacroiliac joints occurs in 21% of acne fulminans cases. We present the case of a 18-year-old male patient in whom acne fulminans evolved from acne vulgaris grade IV and after inflammation resolution started treatment with oral isotretinoin. Within a 30-day period of retinoid treatment he presented with back pain followed by rapid, progressive inability to deambulate.

【 授权许可】

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