Primary cutaneous anaplastic large-cell lymphoma - case report

Anais Brasileiros de Dermatologia

Luciana Silveira Rabello De Oliveira¹  Madeleyne Palhano Nobrega¹  Maira Gomes Monteiro¹  Wagner Leite De Almeida¹ 

关键词: Lymphoma;    large-cell;    anaplastic;    Lymphoma;    primary cutaneous anaplastic large cell;    Lymphoma;    T-cell;    Lymphoma;    T-cell;    cutaneous;    Linfoma anaplásico de células grandes;    Linfoma anaplásico cutâneo primário de células grandes;    Linfoma cutâneo de células T;    Linfoma de células T;   

DOI  :  10.1590/abd1806-4841.20131731

来源: SciELO

【 摘 要 】

Primary cutaneous anaplastic large-cell lymphoma is part of the spectrum of CD30+ lymphoproliferative cutaneous processes, characterized by single or multifocal nodules that ulcerate, are autoregressive and recurrent. Extracutaneous dissemination may occur, especially to regional lymph nodes. Histology shows a diffuse, non-epidermotropic infiltrate , anaplastic large lymphoid cells of immunohistochemistry CD30+, CD4+, EMA-/+, ALK-, CD15- and TIA1-/+. Prognosis is good and does not depend on lymphatic invasion. Radiotherapy, removal of the lesion and/or low-dose methotrexate are the treatments of choice. The present study reports the case of a 57-year-old-woman presenting Primary cutaneous anaplastic large-cell lymphoma with multifocal lesions. The pacient evolved with pulmonary involvement 7 years later. She showed a good response to the treatment with low-dose methotrexate prescribed weekly.

【 授权许可】

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