Exacerbation of recalcitrant cutaneous sarcoidosis with adalimumab - a paradoxical effect? A case report

Anais Brasileiros de Dermatologia

Guida Santos¹  Lourdes Emerenciano Sousa¹  Alexandre Miguel Bruno Lopes João¹ 

关键词: Biological agents;    Biological treatment;    Sarcoidosis;    Tumor necrosis factor-alpha;    Agentes biológicos;    Fator de necrose tumoral alfa;    Sarcoidose;    Tratamento biológico;   

DOI  :  10.1590/abd1806-4841.20132487

来源: SciELO

【 摘 要 】

The paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab.

【 授权许可】

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