Rosai-Dorfman disease presenting with extensive cutaneous manifestation - Case report

Anais Brasileiros de Dermatologia

Paula Azevedo Borges Leal¹  Adrilena Lopes Adriano¹  Marcelle Parente Breckenfeld¹  Igor Santos Costa¹  Antônio Renê Diógenes De Sousa¹  Heitor De Sá Gonçalves¹ 

关键词: Emperipolesis;    Histiocytosis;    Histiocytosis;    non-langerhans-cell;    Histiocytosis;    sinus;    Emperipolese;    Histiocitose;    Histiocitose sinus;    Histiocitose de células não Langerhans;   

DOI  :  10.1590/S0365-05962013000200014

来源: SciELO

【 摘 要 】

Rosai-Dorfman disease is a benign, self-limited, idiopathic proliferative histiocytic disorder. It was first described in 1969 by Rosai and Dorfman. In its typical form the disease is characterized by extensive cervical lymphadenopathy associated with fever, polyclonal gammopathy and leukocytosis with neutrophilia. The skin is the most common site affected. Extranodal manifestations have been reported in 43% of cases. In this study, we report an atypical case of Rosai-Dorfman disease in a female with massive cutaneous manifestation on the thigh, associated with a minimal lymphadenopathy limited to the regional inguinal lymph nodes.

【 授权许可】

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