Clear cell acanthoma of the areola and nipple: clinical, histopathological, and immunohistochemical features of two Brazilian cases*

Anais Brasileiros de Dermatologia

Rossana Ruth Garcia Da Veiga¹  Renata Silva Barros¹  Josie Eiras Bisi Dos Santos¹  José Maria De Castro Abreu Junior¹  Maraya De Jesus Semblano Bittencourt¹  Mario Fernando Ribeiro De Miranda¹ 

关键词: Acanthoma;    Breast;    Eczema;    Histology;    Nipples;    Acantoma;    Eczema;    Histologia;    Mama;    Mamilos;   

DOI  :  10.1590/S0365-05962013000100010

来源: SciELO

【 摘 要 】

Clear cell acanthoma or Degos' acanthoma is a distinct disease concerning its clinical, histopathological, and immunohistochemical features. Its pathologic nature - whether neoplastic or reactive - is still under dispute among researchers. The disease shows a chronic course and often presents with a single papulonodular lesion on the lower limbs of adults. However, cases with multiple lesions, sometimes occurring in an eruptive fashion, and with clear variation in the size and shape of the cutaneous lesions have been reported. So far, five cases in which the lesions were exclusively located in the nipple area have been reported, all in Korean women. Four of these cases mimicked eczema and one, a polypoid nodule. The aim of this article is to present clinical, histopathological, and immunohistochemical features of two additional cases in Brazilian women with similar nipple topography.

【 授权许可】

CC BY-NC   
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