Anais Brasileiros de Dermatologia | |
HLA-B27 frequency in a group of patients with psoriatic arthritis | |
Danilo Garcia Ruiz2  Mário Newton Leitão De Azevedo1  Omar Lupi1  | |
[1] ,Federal University of Rio de Janeiro | |
关键词: Arthritis; psoriatic; HLA-B27 antigen; Spondylarthropathies; Antígeno HLA-B27; Artrite psoriásica; Espondiloartropatias; | |
DOI : 10.1590/S0365-05962012000600004 | |
来源: SciELO | |
【 摘 要 】
BACKGROUND: HLA-B27 is associated with spondyloarthritis, a group of diseases that includes psoriatic arthritis. OBJECTIVES: To describe the HLA-B27 frequency in a group of Brazilian patients with psoriatic arthritis and correlate its presence or absence with their clinical manifestations. METHODS: Cross-sectional study with 44 psoriatic arthritis patients of a Rheumatology clinic. Demographic and social data were recorded, as were skin and joints clinical examination. HLA-B27 was tested. All data were processed descriptively and comparatively by appropriate software. Parametric and non parametric tests were used with 5% statistical significance. RESULTS: HLA-B27 was negative in 32 of the 44 patients (72,7%). Most of them were male, Caucasian, living in Rio de Janeiro, with plaque type psoriasis and average age of 52,9 years. There was statistical significant correlation between positive HLA-B27 and male gender (p=0,004). Negative HLA-B27 had a tendency to correlate with hands and wrists arthritis (p=0,07). There was an inverse significant correlation between HLA values and Schöber's test (p=0,02). CONCLUSION: Although HLA-B27 is negative in most of patients, it is significantly associated to male gender and inversely correlated with Schöber's test.
【 授权许可】
CC BY-NC
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202005130131213ZK.pdf | 83KB | download |