Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs

Anais Brasileiros de Dermatologia

Ana Rita Travassos²  João Borges-costa¹  João Raposo¹  Luís Soares Almeida¹  Paulo Filipe¹ 

[1],Santa Maria Hospital North Lisbon Hospital Center University Dermatology ClinicLisbon,Portugal

关键词: Granuloma;    Lymphoma;    T-Cell;    peripheral;    Recurrence;    Granuloma;    Linfoma de células T periférico;    Recidiva;   

DOI  :  10.1590/S0365-05962012000500018

来源: SciELO

【 摘 要 】

The presence of granulomas in the skin of T-cell lymphoma patients is a rare but well-known phenomenon. The authors present the case of a 44-year-old Caucasian male, with a previously treated peripheral T-cell lymphoma, with cutaneous infiltration and extensive dyschromia on his lower limbs. Skin biopsies revealed the presence of sarcoid granulomas associated with the recurrence of the lymphoma, confirmed by immunostaining and molecular analysis. Although a new scheme of chemotherapy was started, he died 18 months later. There are two different patterns of skin granulomas associated with lymphoma: granulomatous infiltrates admixed with neoplastic cells and cutaneous granulomas constituting a nonspecific manifestation of the underlying lymphoma, but presently there is no evidence supporting their relationship with lymphoma prognosis.

【 授权许可】

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