Calciphylaxis, a diagnostic and therapeutic challenge: report of a successful case

Anais Brasileiros de Dermatologia

Eduardo Vinicius Mendes Roncada²  Marilda Aparecida Milanez Morgado De Abreu²  Mayra Falcão Pereira¹  Claúdia Cardoso Macedo De Oliveira²  Gisele Alborghetti Nai¹  Deusita Fernandes Gandia Soares² 

[1] ,University of the West Paulista Region Regional Hospital of Presidente Prudente Dermatology ServiceSão Paulo SP ,Brazil

关键词: Blood vessels;    Calcium metabolism disorders;    Hyperparathyroidism;    secondary;    Ischemia;    Renal insufficiency;    chronic;    Distúrbios do metabolismo do cálcio;    Hiperparatireoidismo secundário;    Insuficiência renal crônica;    Isquemia;    Vasos sanguíneos;   

DOI  :  10.1590/S0365-05962012000500014

来源: SciELO

【 摘 要 】

Calciphylaxis, also known as calcific uremic arteriolopathy, is a severe complication often observed in patients with hyperparathyroidism secondary to chronic renal failure, which occurs mainly in women. It is characterized by ischemic tissue loss secondary to progressive vascular compromise. This is a rare and severe condition and its pathogenesis is unclear. The best treatment is prevention, especially in order to maintain adequate levels of calcium and phosphorus. We describe a case of this disease in a patient with hyperparathyroidism secondary to chronic renal failure who underwent medical treatment, surgical debridement and total skin autografts, with resolution of symptoms after 6 months.

【 授权许可】

CC BY-NC   
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