Autoimmune thyroiditis presenting as interstitial granulomatous dermatitis

Anais Brasileiros de Dermatologia

Joana Antunes²  David Pacheco²  Ana Rita Travassos²  Luís Miguel Soares-almeida¹  Paulo Filipe¹  Manuel Sacramento-marques¹ 

[1] ,Hospital Center North Lisbon Santa Maria Hospital Dermatology ServiceLisbon,Portugal

关键词: Dermatitis;    Granulomatous disease;    chronic;    Thyroiditis;    Thyroiditis;    autoimmune;    Dermatite;    Doença granulomatosa crônica;    Tireoidite;    Tireoidite auto-imune;   

DOI  :  10.1590/S0365-05962012000500013

来源: SciELO

【 摘 要 】

A 54-year-old female presented with recurrent, widespread, erythematous, painful plaques, over a 3-month period. Skin biopsy was compatible with interstitial granulomatous dermatitis. Additional investigation revealed hypothyroidism and positive anti-thyroid antibodies. Normalization of thyroid function and high-potency topical corticosteroids provided only transitory improvement of the dermatosis. Interstitial granulomatous dermatitis is a histologic inflammatory reaction, with variable cutaneous expression. It has been reported in association with several drugs, lymphoproliferative diseases and autoimmune disorders, such as rheumatoid arthritis, systemic lupus erythematosus and vasculitis, but association with autoimmune thyroiditis is rare. Optimal therapy for this condition is yet to be established, but topical corticosteroids have been a mainstay of treatment. In most cases, this disease is characterized by flares and remissions.

【 授权许可】

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