Periungual capillaroscopy in psoriasis

Anais Brasileiros de Dermatologia

Camila Ferrari Ribeiro¹  Elisa Beatriz Dalledone Siqueira¹  Ana Paula Holler¹  Lincoln Fabrício²  Thelma Larocca Skare² 

[1] ,Evangelical College of Paraná Evangelical University Hospital of Curitiba Department of DermatologyCuritiba PR ,Brazil

关键词: Capillaries;    Microscopic angioscopy;    Psoriasis;    Psoriatic arthritis;    Angioscopia microscópica;    Artrite psoriásica;    Capilares;    Psoríase;   

DOI  :  10.1590/S0365-05962012000400005

来源: SciELO

【 摘 要 】

BACKGROUND: Nailfold capillaroscopy is a useful technique for evaluating changes in microcirculation. OBJECTIVE: To investigate changes at nailfold capillaroscopy in psoriatic patients compared with controls. METHODS: Nailfold capillaroscopy was performed in 46 psoriatic patients and 50 controls to assess microscopic morphological changes, capillary density and the presence of areas with devascularization. RESULTS: Patients with psoriasis had lower capillary density (p=0.0005), increased avascular areas (p=0.0035) and an increased number of morphologically abnormal capillaries (coiled, p<0.0001) compared to controls. No association was found between capillary density and the duration of the disease (p = 0.92) or the extent of skin involvement, as measured by the psoriasis area and severity index (PASI) score (p = 0.59). The presence of avascular areas was more common in psoriatic individuals whose nails were affected by the condition (p = 0.047). CONCLUSION: Patients with psoriasis have decreased capillary density and a greater presence of morphologically abnormal capillaries when compared to controls.

【 授权许可】

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