Prevalence of autoantibodies in a group of hereditary angioedema patients

Anais Brasileiros de Dermatologia

Sergio Duarte Dortas Junior²  Solange Oliveira Rodrigues Valle¹  Soloni Afra Pires Levy¹  Rosangela P. Tortora¹  Augusto Tiaqui Abe¹  Gisele Viana Pires¹  José Angelo De Souza Papi¹  Alfeu Tavares França¹ 

[1] ,Hospital Geral de Nova Iguaçu Medical Residency Program in Internal Medicine Nova Iguaçu RJ ,Brazil

关键词: Angioedemas;    hereditary;    Autoantibodies;    Hereditary angioedema type III;    Hereditary angioedema types I and II;    Prevalence;    Angioedemas hereditários;    Angioedema hereditário tipos I e II;    Angioedema hereditário tipo III;    Auto-anticorpos;    Prevalência;   

DOI  :  10.1590/S0365-05962012000200030

来源: SciELO

【 摘 要 】

Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.

【 授权许可】

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