Pharmacological adherence to oral anticoagulant and factors that influence the international normalized ratio stability

Revista Latino-Americana de Enfermagem

Christiane Wahast Ávila²  Graziella Badin Aliti¹  Maria Karolina Ferreira Feijó²  Eneida Rejane Rabelo¹ 

[1] ,Universidade Federal do Rio Grande do Sul Escola de Enfermagem Hospital de Clínicas de Porto Alegre RS ,Brazil

关键词: Anticoagulants;    International Normalized Ratio;    Monitoring;    Ambulatory;    Anticoagulantes;    Coeficiente Internacional Normatizado;    Monitorização Ambulatorial;    Anticoagulantes;    Relación Normalizada Internacional;    Monitoreo Ambulatorio;   

DOI  :  10.1590/S0104-11692011000100004

来源: SciELO

【 摘 要 】

Cross-sectional study developed to relate the international normalized ratio (INR), used as a parameter to monitor the levels of blood clotting, stability to adherence, age, level of education, socioeconomic level, interaction with other drugs, comorbidities, vitamin K intake, anticoagulation time and drug cost. 156 patients were included, mean age 57±13 years, (53.8%) male, 61 (39.1%) had high adherence, 91 (58.3%) medium and 4 (2.6%) low adherence to treatment, 117 (75%) had INR stability up to 50% and 39 (25%) > 75%, patients with shorter time of anticoagulation presented higher stability, those who spent less on the drug remained more stable and had better adherence. It was concluded that more than 90% of patients had high and medium adherence and that the anticoagulation time and drug cost were the factors related to the anticoagulation stability.

【 授权许可】

CC BY   
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