Infusion of Hematopoietic Stem Cells: Types, Characteristics, Adverse and Transfusion Reactions and the Implications for Nursing

Revista Latino-Americana de Enfermagem

Ana Carolina De Jesus Vieira Curcioli¹  Emilia Campos De Carvalho² 

[1] ,Universidade de São Paulo Escola de Enfermagem de Ribeirão PretoSP ,Brazil

关键词: Hematopoietic Stem Cell Transplantation;    Blood Component Transfusion;    Nursing;    Transplante de Células-Tronco Hematopoéticas;    Transfusão de Componentes Sanguíneos;    Enfermagem;    Trasplante de Células Madre Hematopoyéticas;    Transfusión de Componentes Sanguíneos;    Enfermería;   

DOI  :  10.1590/S0104-11692010000400009

来源: SciELO

【 摘 要 】

Hematopoietic stem cell infusion is an important procedure in Hematopoietic Stem Cell Transplantation (HSCT). This study identifies transfusion and other adverse reactions that can occur during infusion and the nursing care related to the procedure. This epidemiologic study used transplantations performed between 2006 and 2008. A total of 166 transplantations were performed: 114 were autologous, 47 allogeneic and five haploidentical. Three transfusion reactions and 96 adverse reactions were observed. Adverse reactions were related to the presence of cryoprotectant, though the infusion rate and quantity of infused cryoprotectant were not related to the occurrence of reactions. The products were fresh and infused within the recommended time when transfusion reactions occurred. In regard to cell source, lower engraftment time was found in peripheral blood. Nursing documentation is relevant for patients' safety as well to planning an infusion in order to minimize the occurrence of reactions.

【 授权许可】

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