Histopathological findings and detection of parasites in the eyes of dogs infected naturally with Leishmania chagasi

Ciência Rural

Fábio Luiz Da Cunha Brito²  José Luiz Laus¹  Wagner Luiz Tafuri¹  Maria Marta Figueiredo¹  Valdemiro Amaro Silva Júnior¹  Frederico Celso Lyra Maia¹  Leucio Câmara Alves¹ 

[1] ,ProimagemRecife PE ,Brasil

关键词: canine;    Leishmaniasis;    ocular abnormalities;    histopathology;    immunohistochemistry;    cão;    Leishmania;    anormalidades oculares;    histopatologia;    imunoistoquímica;   

DOI  :  10.1590/S0103-84782010005000079

来源: SciELO

【 摘 要 】

The objective of the present study was to investigate the histopathological alterations and detection of parasites that occur in the eyes of dogs naturally infected with Leishmania chagasi. The eyes of 25 dogs with a positive parasitological and serological exam for L. chagasi were submitted to routine ophthalmic examination. Fragments were obtained from the eyeball and were analyzed by immunohistochemistry and histopathology. Among the structures studied, the conjunctiva of the third eyelid was the tissue most frequently stained for L. chagasi. Histopathological analysis revealed a predominantly mononuclear inflammatory infiltrate whose intensity ranged from discrete to intense in the various ocular structures. Vascular congestion and perivasculitis were also observed. The histopathological alterations that occur in the eyeball of dogs with visceral leishmaniasis might be related to the presence of antibodies.

【 授权许可】

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