In vitro evaluation of the antimicrobial activity of five root canal sealers

Brazilian Dental Journal

Brenda Paula Figueiredo De Almeida Gomes¹  José Assis Pedroso¹  Rogério Castilho Jacinto¹  Morgana Eli Vianna¹  Caio Cezar Randi Ferraz¹  Alexandre Augusto Zaia¹  Francisco José De Souza-filho¹ 

[1] ,UNICAMP Dental School of Piracicaba Area of EndodonticsPiracicaba SP ,Brazil

关键词: antimicrobial activity;    root canal sealers;    bacteria;    endodontics;   

DOI  :  10.1590/S0103-64402004000100006

来源: SciELO

【 摘 要 】

The aim of the present study was to analyze the antimicrobial properties of five endodontic sealers: Endo Fill, Endomethasone, Endomethasone N, Sealer 26 and AH-Plus, against the following microorganisms: Candida albicans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus sanguis and Actinomyces naeslundii. The sealers were tested immediately, 24 h, 48 h and 7 days after manipulation.The direct contact method through the observation of the microbial growth in liquid medium and the agar diffusion test were used to evaluate the antimicrobial properties of the sealers. The results, in both methodologies used, showed that immediately after manipulation, Endo-Fill and Endomethasone demonstrated the highest antimicrobial activity, with no statistically significant difference between them. Sealer 26 demonstrated the lowest antimicrobial activity. At all other times after manipulation, there were no statistically significant differences among all the sealers tested. In conclusion, none of the sealers totally inhibited the growth of the microorganisms. Furthermore, the antimicrobial activity of each sealer decreased with time and was dependent upon the microbial susceptibility to them.

【 授权许可】

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