Obstructive sleep apnea: acute effects of CPAP on polyssonographic variables

Fisioterapia em Movimento

Marco Colomé Beck¹  Chaiane Facco Piccin¹  Luiz Carlos Alves De Oliveira¹  Fabrício Scapini¹  Reinaldo Fernando Coser Neto¹  Antônio Marcos Vargas Da Silva¹ 

关键词: Obstructive sleep apnea;    Continuous positive airway pressure;    Polysomnography;    Apneia obstrutiva do sono;    Pressão positiva contínua nas vias aéreas;    Polissonografia;   

DOI  :  10.1590/0103-5150.028.002.AO02

来源: SciELO

【 摘 要 】

Introduction The use of non-invasive ventilation in the form of continuous positive airway pressure (CPAP) is among the main therapeutic options for patients with obstructive sleep apnea (OSA). Yet the effects of CPAP obtained on the first night of use are underreported. Objective To evaluate the acute effects of CPAP on polysomnographic variables in patients with OSA. Materials and methods This study is a case series with 31 patients (55.8 ± 11.4 years; 22 men) in the initial phase of CPAP treatment. The subjects were evaluated by means of polysomnography with and without CPAP (10.2 ± 3.1 cmH2O) and without CPAP, on different days, by means of the following variables: sleep stages 1, 2 and 3 (N1, N2 and N3), rapid eye movement (REM) sleep, apnea and hypopnea index (AHI), AHI in REM sleep (AHIREM) and the micro-arousal index (MAI). Results The use of CPAP resulted in a reduction of N2 (p < 0.001), AHI (p < 0.001), AHIREM (p < 0.001) and MAI (p = 0.001). There was an increase in N3 (p = 0.006) and REM sleep (p < 0.001) during the night with use of CPAP. Conclusion This study demonstrated that, from the first night of use by patients with OSA, CPAP promotes greater balance between sleep phases, and improves sleep quality. These results should be presented to patients and their families in order to encourage greater adherence in the initial phase of treatment with CPAP.

【 授权许可】

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