Journal of the Brazilian Chemical Society | |
Development of a Selective and Sensitive Sensor for Urate Determination Based on Tris(1,10-phenantroline)copper(II) Bis(tetracyanoquinodimethanide) Adsorbed on Carbon Nanotubes | |
Dilton M. Pimentel1  Fernando M. De Oliveira1  Wallans T. P. Dos Santos1  Lauro T. Kubota1  Flávio S. Damos1  Rita C. S. Luz1  | |
关键词: Cu(phen)3(TCNQ)2; functionalized carbon nanotubes; urate; | |
DOI : 10.5935/0103-5053.20150184 | |
来源: SciELO | |
【 摘 要 】
The present work describes the development of a selective electrochemical sensor for urate based on tris(1,10-phenantroline)copper(II) bis(tetracyanoquinodimethanide) (Cu(phen)3(TCNQ)2) adsorbed on multi-walled carbon nanotubes (CNT). The composite material was characterized by infrared spectroscopy, scanning electron microscopy, and electrochemical impedance spectroscopy. The composite material showed an excellent electrocatalytic activity toward oxidation of urate. The heterogeneous charge transfer rate constant (k’) between the analyte and the sensor was determined using linear sweep voltammetry experiments. The composite material shows a linear range from 5 up to 2500 µmol L-1 with limit of detection of 1.05 µmol L-1 and limit of quantification of 3.50 µmol L-1. The high sensitivity and selectivity of the sensor for urate was sufficient for its determination in biological fluids. Finally, the proposed sensor was successfully applied in urine samples.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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