Solvent-free oxidation of secondary alcohols to carbonyl compounds by 1, 3-dibromo-5, 5-dimethylhydantoin (DBDMH) and 1, 3-dichloro-5, 5-dimethylhydantoin (DCDMH)

Journal of the Brazilian Chemical Society

Ardeshir Khazaei²  Fatemeh Abbasi²  Maryam Kianiborazjani¹  Shahnaz Saednia¹ 

[1] ,Bu-Ali Sina University Department of Organic Chemistry Faculty of ChemistryHamedan,Iran

关键词: oxidation;    carbonyl compound;    dibromo dimethylhydantoin;    dichloro dimethylhydantoin;    solvent free;   

DOI  :  10.5935/0103-5053.20130304

来源: SciELO

【 摘 要 】

Aldehydes and ketones are important intermediates, especially for the construction of carbon-skeletons. The oxidation of alcohols is so important that a large number of methods and reagents have been reported for this purpose. N-halo reagents are widely used in organic synthesis and as a continuation of our interest in the application of N-halo compounds in organic synthesis, dibromo dimethylhydantoin (DBDMH) and dichloro dimethylhydantoin (DCDMH) were used for the oxidation of alcohols and our ongoing work on development of highly efficient oxidation protocols. We observed the oxidation of secondary alcohols with stoichiometric amounts of DBDMH and DCDMH under solvent-free conditions in the range of temperature 70-80 ºC.

【 授权许可】

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