New hybrid material based on layered double hydroxides and biogenic silver nanoparticles: antimicrobial activity and cytotoxic effect

Journal of the Brazilian Chemical Society

Priscyla D. Marcato²  Natália V. Parizotto²  Diego Stéfani T. Martinez²  Amauri J. Paula²  Iasmin R. Ferreira¹  Patrícia S. Melo¹  Nelson Durán¹  Oswaldo L. Alves² 

[1] ,Universidade de Campinas Laboratório de Química do Estado Sólido Campinas SP ,Brazil

关键词: silver nanoparticles;    hydrotalcite;    antimicrobial activity;    cytotoxicity;   

DOI  :  10.5935/0103-5053.20130034

来源: SciELO

【 摘 要 】

Layered double hydroxides (LDHs) have been widely investigated due to their several applications in the material and biotechnology industries. The combination of silver nanoparticles with biocompatible LDH material can create a new hybrid material with new properties. In this work, biogenic silver nanoparticles (AgNPbio) were associated with Mg-Al LDH to obtain the hybrid material LDH-AgNPbio. The new hybrid material obtained was characterized by X-ray diffractometry (XRD), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS), transmission electron microscopy (TEM), inductively coupled plasma optical emission spectrometry (ICP-OES) and Fourier transform infrared spectroscopy (FTIR). LDH was efficient to absorb silver nanoparticles due to an opposite surface charge between AgNPbio (ζ = -13.2 mV) and LDH (ζ = +3.2 mV). Furthermore, AgNPbio was not lixiviated from LDH-AgNPbio, even after five washes, indicating a strong interaction. An important property of this hybrid material was its antimicrobial activity against Staphylococcus aureus and Escherichia coli and absence of cytotoxic effect to fibroblast cell (V79). This hybrid material is an interesting and promising nanobiocomposite for biomedical and cosmetic applications.

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