An efficient methodology for the synthesis of 3-styryl coumarins

Journal of the Brazilian Chemical Society

Sérgio M. A. Martins²  Paula C. S. Branco¹  António M. D. R. L. Pereira² 

[1] ,Universidade de Évora Centro de Química Departamento de QuímicaÉvora,Portugal

关键词: 3-vinyl coumarin;    3-styryl coumarin;    Heck reaction;    palladium;    fluorescent dyes;   

DOI  :  10.1590/S0103-50532012000400014

来源: SciELO

【 摘 要 】

Regioselective and highly efficient Heck arylation of 3-vinyl-6,7-dimethoxycoumarin has been developed to afford 3-styryl coumarins in good to very high yields. The increase in conjugation reflects on the absorbance of the synthesized compounds revealing all pronounced bathochromic shifts and hyperchromic effects.

【 授权许可】

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