Total synthesis of 1-hydroxydehydroherbarin and ascomycones A, B, naphthoquinone antibiotics

Journal of the Brazilian Chemical Society

Wen-kai Dong¹  Xiong Huang¹  Dong-cheng Xu¹  Xin-sheng Li¹  Jian-wu Xie¹ 

[1] ,Zhejiang Normal University Department of Chemistry and Life Science ,China

关键词: pyranonaphthoquinone;    1-hydroxydehydroherbarin;    ascomycones A;    B;    antibiotics;    total synthesis;   

DOI  :  10.1590/S0103-50532012000200013

来源: SciELO

【 摘 要 】

The first total synthesis of 1-hydroxydehydroherbarin and ascomycones A and B is reported. The biologically interesting ascomycones A and B were obtained in 18% overall yield starting from 3-chloro-2,5-dimethoxybenzaldehyde as building block.

【 授权许可】

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