Synthesis, antimicrobial and cytotoxicity studies of some novel modified Strobilurin derivatives

Journal of the Brazilian Chemical Society

Ajjanna M Sridhara²  Kallam R. Venugopala Reddy¹  Jathi Keshavayya¹  Dasannana Malige S Ambika¹  Vadiraj S Gopinath²  Prosenjit Bose²  Sanath Kumar Goud²  Sanenahalli K Peethambar¹ 

[1] ,Advinus Therapeutics Pvt. LtdBangalore,India

关键词: phthalazin-1(2H)-one;    β-methoxyacrylate;    strobilurins;    isoxazoline;   

DOI  :  10.1590/S0103-50532011000500006

来源: SciELO

【 摘 要 】

A series of some new 3-isoxazoline substituted methyl-3-methoxy-2-(4-oxo-3,4-dihydrophthalazin-1-yl)prop-2-enoate derivatives were designed and synthesized from methyl-(4-oxo-3,4-dihydrophthalazin-1-yl)acetate, which in turn was prepared from phthalic anhydride. The structures of synthesized new compounds were characterized by spectral data and studied for their antimicrobial activities and cytotoxicity. Several of these compounds showed good antimicrobial activity

【 授权许可】

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