Eco-friendly synthesis of 2-substituted benzothiazoles catalyzed by cetyltrimethyl ammonium bromide (CTAB) in water

Journal of the Brazilian Chemical Society

Xiao-liang Yang¹  Chun-mei Xu¹  Shao-miao Lin¹  Jiu-xi Chen¹  Jin-chang Ding¹  Hua-yue Wu¹  Wei-ke Su¹ 

[1] ,Wenzhou University College of Chemistry and Materials Engineering ,P. R. China

关键词: 2-alkylbenzothiazole;    2-arylbenzothiazole;    2-arylformylbenzothiazole;    cetyltrimethyl ammonium bromide (CTAB);    water;   

DOI  :  10.1590/S0103-50532010000100007

来源: SciELO

【 摘 要 】

A series of 2-substituted benzothiazoles have been synthesized by the condensation of 2-aminothiophenol with aldehydes (RCHO: R = Alkyl, Aryl, Heteroaryl, 2-Arylformyl) in the presence of a catalytic amount of cetyltrimethyl ammonium bromide (CTAB) "on water" by a one-pot procedure without additional organic solvents and oxidants. Thereinto, 2-alkylbenzothiazoles were synthesized in high yields and 2-arylformylbenzothiazoles were obtained from the condensation of 2-aminothiophenol with arylformyl aldehydes for the first time using the present protocol.

【 授权许可】

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