Silica-supported dichlorophosphate: a recoverable cyclodehydrant for the eco-friendly synthesis of 2,5-disubstituted 1,3,4-oxadiazoles under solvent-free and microwave irradiation conditions

Journal of the Brazilian Chemical Society

Zheng Li¹  Anguo Zhu¹  Xuerong Mao¹  Xiunan Sun¹  Xue Gong¹ 

[1] ,Northwest Normal University College of Chemistry and Chemical Engineering Gansu Key Laboratory of Polymer MaterialsLanzhou Gansu ,China

关键词: silica-supported dichlorophosphate;    diacylhydrazine;    1;    3;    4-oxadiazole;    microwave irradiation;    solvent-free synthesis;   

DOI  :  10.1590/S0103-50532008000800024

来源: SciELO

【 摘 要 】

A series of symmetrical and unsymmetrical 2,5-disubstituted 1,3,4-oxadiazoles were efficiently synthesized from the cyclodehydration of diacylhydrazines by using silica-supported dichlorophosphate as a recoverable cyclodehydrant in solvent-free medium under microwave irradiation. This protocol has advantages of no corrosion, no environmental pollution, accelerated rate, high yield and simple work-up procedure.

【 授权许可】

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