Journal of the Brazilian Chemical Society | |
Chemiluminescence determination of mezlocillin by the luminol-potassium periodate system | |
Wen Bing Shi1  Ji Dong Yang1  | |
[1] ,Fuling Normal University Department of Chemisty and Enviroment Science ,P. R. China | |
关键词: chemiluminescence; flow injection; mezlocillin; | |
DOI : 10.1590/S0103-50532008000600019 | |
来源: SciELO | |
【 摘 要 】
A new, simple and sensitive method has been proposed for the determination of mezlocillin. It is based on the enhancement of the chemiluminescence (CL) emission generated from the oxidation of luminol in alkaline medium by postassium periodate. The optimization of the experimental and instrumental variables affecting the CL enhancement effect has been carried out using flow-injection system. In the optimum conditions, the method is efficient to determine mezlocillin in the linear range of 0.01-30×10-6 g mL-1 with a detection limit (3σ) of 3.0×10-9 g mL-1 and the relative standard deviation (RSD) is 1.0% for 1.0×10-6 g mL-1 mezlocillin (n=11). It has been successfully applied to the mezlocillin determination in commercial preparations, synthetic samples and biological fluids formulations.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
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