Sample optimization for rapid identification of nucleosides and bases from ascidian extracts using ESI-MS/MS

Journal of the Brazilian Chemical Society

Renata Takeara¹  Paula C. Jimenez²  Letícia V. Costa-lotufo²  João L. C. Lopes¹  Norberto P. Lopes¹ 

[1] ,Universidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto Departamento de Física e QuímicaRibeirão Preto SP ,Brazil

关键词: natural products;    ESI-MS/MS;    ascidian;    nucleosides;    glycosylamines;   

DOI  :  10.1590/S0103-50532007000500027

来源: SciELO

【 摘 要 】

Electrospray ionization tandem mass spectrometry (ESI-MS/MS) method was developed for identification of nucleosides and bases in extracts of ascidians. For this study a systematic sample preparation associated with the fragmentation pattern of a series of nucleosides and bases using ESI-MS/MS was done. These approaches constitute powerful analytical tools for rapid screening and structural assignment of nucleosides and bases in ascidian extracts.

【 授权许可】

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