Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues

Journal of the Brazilian Chemical Society

Caridad R. Rodríguez²  Yohan I. Villalobos²  Esther A. Becerra²  Francisco C. Manchado²  Deysma C. Herrera²  Marco A. T. Zullo¹ 

[1] ,University of Havana Faculty of Chemistry Natural Products LaboratoryHabana,Cuba

关键词: steroids;    brassinosteroid analogues;    diosgenin;   

DOI  :  10.1590/S0103-50532003000300022

来源: SciELO

【 摘 要 】

Three new spirostanic brassinosteroid analogues have been synthesized for the first time from diosgenin: (25R)-2alpha,3alpha-epoxy-5alpha-hydroxyspirostan-6-one (3), (25R)-2beta,3alpha,5alpha-trihydroxyspirostan-6-one (5) and (25R)-2beta-methoxy-3alpha,5alpha-dihydroxyspirostan-6-one (6). In the radish hypocotyl elongation and cotyledon expansion bioassay compound 3 showed plant growth promoting activity whereas 6 was shown to be phytotoxic.

【 授权许可】

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