Direct electron transfer: an approach for electrochemical biosensors with higher selectivity and sensitivity

Journal of the Brazilian Chemical Society

Renato S. Freire¹  Christiana A. Pessoa¹  Lucilene D. Mello¹  Lauro T. Kubota¹ 

[1] ,Universidade Estadual de Campinas Instituto de Química Campinas SP ,Brazil

关键词: direct electron transfer;    electrochemical biosensors;    electrodes;    redox enzymes;    self-assembled monolayer;   

DOI  :  10.1590/S0103-50532003000200008

来源: SciELO

【 摘 要 】

The most promising approach for the development of electrochemical biosensors is to establish a direct electrical communication between the biomolecules and the electrode surface. This review focuses on advances, directions and strategies in the development of third generation electrochemical biosensors. Subjects covered include a brief description of the fundamentals of the electron transfer phenomenon and amperometric biosensor development (different types and new oriented enzyme immobilization techniques). Special attention is given to different redox enzymes and proteins capable of electrocatalyzing reactions via direct electron transfer. The analytical applications and future trends for third generation biosensors are also presented and discussed.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License