Effectiveness of epicardial atrial pacing using a bipolar steroid-eluting endocardial lead with active fixation in an experimental model

Acta Cirurgica Brasileira

Sávia Christina Pereira Bueno¹  Wagner Tetsuji Tamaki¹  Marcelo Fiorelli Alexandrino Da Silva¹  Cristiane Maciel Zambolim²  Kátia Regina Da Silva¹  Martino Martinelli Filho¹  Roberto Costa¹ 

[1] ,USP Clinics Hospital Sao Paulo SP ,Brazil

关键词: Pacemaker;    Artificial;    Surgical Procedures;    Operative;    Electrodes;    Implanted;    Transverse Sinuses;    Animal Experimentation;    Swine;   

DOI  :  10.1590/S0102-86502013000700011

来源: SciELO

【 摘 要 】

PURPOSE: To assess the effectiveness of bipolar epicardial atrial pacing using an active fixation bipolar endocardial lead implanted on the atrial surface in an experimental model. METHODS: A total of ten Large White adult pigs underwent pacemaker implantation under general anesthesia. Atrial pacing and sensing parameters were obtained at the procedure, immediate postoperative period and on the 7th and the 30th postoperative in unipolar and bipolar configurations. RESULTS: All procedures were successfully performed. There were no perioperative complications and no early deaths. Atrial pacing and sensing parameters for both unipolar and bipolar modes remained stable throughout the study. We observed a progressive increase in atrial thresholds, ranging from 0.49 ± 0.35 (at implantation) to 1.86 ± 1.31 volts (30th postoperative day), in unipolar mode. Atrial impedance measurements decreased slightly over time, ranging from 486.80 ± 126.35 Ohms (at implantation) to 385.0 ± 80.52 Ohms (30th postoperative day). Atrial sensing measures remained stable from the immediate postoperative period until the end of the study. CONCLUSION: The bipolar active fixation endocardial lead implanted epicardially can provide stable conditions of pacing and sensing parameters throughout the postoperative follow-up.

【 授权许可】

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