Spinal anesthesia for elective ceasarean section: use of different doses of hyperbaric bupivacaine associated with morphine and clonidine

Acta Cirurgica Brasileira

Angélica De Fátima De Assunção Braga²  José Aristeu Fachini Frias²  Franklin Sarmento Da Silva Braga¹  Rosa Inês Costa Pereira¹  Stella Marys Meirelles Campos Titotto¹ 

[1] ,UNICAMP Department of Anesthesiology Campinas SP ,Brazil

关键词: Adrenergic alpha-2 Receptor Agonists;    Clonidine;    Analgesics;    Opioid;    Morphine;    Cesarean Section;   

DOI  :  10.1590/S0102-86502013000100005

来源: SciELO

【 摘 要 】

PURPOSE: To comparatively study the efficacy and maternal and fetal side-effects of two doses of bupivacaine associated with morphine and clonidine, administered by the subarachnoid route for cesarean section. METHODS: The study included 66 pregnant women at term, distributed into two groups. GI: bupivacaine 8.0 mg (1.6mL) + clonidine 75µg (0.5mL) + morphine 100µg (1.0mL) and GII: bupivacaine 10mg (2.0mL) + clonidine 75µg (0.5mL) + morphine 100µg (1.0mL). The following parameters were assessed: onset and maximum level of sensory block; quality of intraoperative and postoperative analgesia; degree and duration of motor block; maternal repercussions and Apgar score. RESULTS: The onset of sensory block, quality of intraoperative analgesia and total duration of analgesia were similar in both groups; maximum extent of sensory block predominated in T4; maximum degree of motor block (Bromage 3); time motor block regression was significantly longer in GII; Hemodynamic, respiratory repercussions, adverse maternal effects and Apgar scores were similar between groups. In both groups, there was a predominance of drowsy or sleeping patients. CONCLUSION: The addition of morphine and clonidine to low doses of hyperbaric bupivacaine produced adequate anesthesia for cesarean section and good postoperative analgesia, without any maternal and fetal repercussions.

【 授权许可】

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