Innovative technique for the study of pneumoperitoneum in the evaluation of abdominal pain after chemical irritation with zymozan

Acta Cirurgica Brasileira

Eduardo Crema²  Bruna Ferrante Silva¹  Pauliana Lamounier E Silva¹  Virmondes Rodrigues Júnior¹  Fernando Cunha¹ 

[1] ,Federal University of Triângulo Mineiro Department of Digestive Surgery Uberaba MG ,Brazil

关键词: Laparoscopy;    Zymosan;    Pneumoperitoneum;    Artificial;    Abdominal Pain;    Mice;    Laparoscopia;    Zimosan;    Pneumoperitônio Artificial;    Dor Abdominal;    Camundongos;   

DOI  :  10.1590/S0102-86502008000300008

来源: SciELO

【 摘 要 】

PURPOSE: To assess the influence of pneumoperitoneum in mice submitted to peritoneal irritation provoked by the biological agent Saccharomyces cerevisae, by counting the number of abdominal contractions elicited. METHODS: To study the effects of pneumoperitoneum analgesic action, 60 mice were divided into two groups: the experimental group, subjected to pneumoperitoneum; and the control group, without pneumoperitoneum. The both groups received intraperitoneal injection of zymosan at a dose of 1mg/0,2ml/mouse. RESULTS: The sum of the number of abdominal contractions of the experimental group (with pneumoperitoneum) was significantly lower than that of the control group (without pneumoperitoneum). In the experimental group, a lower number of contractions occurred in each min compared to the control. CONCLUSION: The observation of the analgesic effect of pneumoperitoneum using CO2 in mice submitted to peritoneal irritation by zymosan was verified.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License