Chronic liver disease prevention strategies and liver transplantation

Acta Cirurgica Brasileira

Anderson Soares Da Silva²  Luciane Loures Dos Santos²  Afonso Dinis Costa Passos²  Ajith Kumar Sankarankutty¹  Ana De Lourdes Candolo Martinelli¹  Orlando De Castro E Silva¹ 

[1] ,USP FMRP Department of Social Medicine,Brazil

关键词: Liver Transplantation;    Hepatitis Virus B;    Hepatitis Virus C;    Chronic Hepatitis;    Cirrose Hepática;    Hepatites Virais;    Hepatite B;    Hepatite C;    Hepatite Crônica;    Prevenção;   

DOI  :  10.1590/S0102-86502006000700018

来源: SciELO

【 摘 要 】

Chronic liver disease is a considerable burden on society, being one of the three main causes of death in certain regions of Africa and Asia. Liver transplant is the only treatment option for cirrhosis, which is the end stage of many chronic liver diseases. This article reviews the preventable causes of cirrhosis and the preventive strategies which could be implemented in order to avoid the catastrophic consequences of cirrhosis. With small variations around the world, 70 to 80% of the end stage liver diseases are caused by excessive alcohol consumption and by viral hepatitis, both of which are potentially preventable. Excessive alcohol consumption has important public health consequences because of its involvement not only with cirrhosis, but also with motor vehicle accidents, unemployment, domestic violence etc. Among the viral causes, Hepatitis Virus B and C have the greatest impact on public health. Effective vaccine is available for Hepatitis Virus B and must be put in use. While a vaccine for Hepatitis Virus C is awaited, effective preventive strategies should be undertaken to avoid the preventable cases of end stage liver disease.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License