Nonalcoholic fatty liver disease and obesity

Acta Cirurgica Brasileira

Wilson Salgado Júnior¹  José Sebastião Dos Santos¹  Ajith Kumar Sankarankutty¹  Orlando De Castro E Silva¹ 

[1] ,USP FMRP Department of Surgery and Anatomy,Brazil

关键词: Nonalcoholic Steatohepatitis;    Hepatic Fibrosis;    Morbid Obesity;    Bariatric Surgery;    Esteato-Hepatite Não Alcoólica;    Fibrose Hepática;    Obesidade Mórbida;    Cirurgia Bariátrica;   

DOI  :  10.1590/S0102-86502006000700017

来源: SciELO

【 摘 要 】

PURPOSE: The aim of this review is to update concepts of the nonalcoholic fatty liver disease (NAFLD) and to establish a relationship between this condition and obesity. METHODS: By means of a comprehensive literature review where special attention was devoted to articles published in the last 5 years, NAFLD is discussed in view of new concepts, diagnosis, staging, and treatment. RESULTS: NAFLD is emerging as one of the main causes of chronic liver disease and it is believed to be the hepatic component of the metabolic syndrome, whose central features include obesity, hyperinsulinemia, peripheral insulin resistance, diabetes, dyslipidemia, and hypertension. The surgical treatment of morbid obesity is one of the options available for the treatment of NAFLD. CONCLUSION: Nonalcoholic fatty liver disease is strongly related with obesity.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License