Effects of intraoperative diltiazem infusion on flow changes in arterial and venous grafts in coronary artery bypass graft surgery

Revista Brasileira de Cirurgia Cardiovascular

Ozan Erdem¹  Mehmet Erdem Memetoğlu¹  Ali İhsan Tekin¹  Ümit Arslan¹  Özgür Akkaya¹  Rasim Kutlu¹  İlhan Gölbaşı¹ 

关键词: Flow Measurements;    Coronary Artery Bypass;    Diltiazem;    Myocardial Revascularization;    Medição de Vazão;    Ponte de Artéria Coronária;    Diltiazem;    Revascularização Miocárdica;   

DOI  :  10.5935/1678-9741.20150045

来源: SciELO

【 摘 要 】

AbstractObjective: This study aimed to show the effects of intra-operative diltiazem infusion on flow in arterial and venous grafts in coronary artery bypass graft surgery.Methods: Hundred fourty patients with a total of 361 grafts [205 (57%) arterial and 156 (43%) venous] underwent isolated coronary surgery. All the grafts were measured by intraoperative transit time flow meter intra-operatively. Group A (n=70) consisted of patients who received diltiazem infusion (dose of 2.5 microgram/kg/min), and Group B (n=70) didn't receive diltiazem infusion.Results: Mean graft flow values of left internal mammary artery were 53 ml/min in Group A and 40 ml/min in Group B (P<0.001). Pulsatility index (PI) values of left internal mammary artery for Group A and Group B were 2.6 and 3.0 respectively (P<0.001). No statistically significant difference was found between venous graft parameters.Conclusion: We recommend an effect of diltiazem infusion in increasing graft flows in coronary artery bypass graft operations.

【 授权许可】

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